Name: RBM15 Polyclonal Antibody (1.2 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: BC006397
  
  Please contact us at for specific academic pricing.
  
  Background
  
  RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t(1,22)(p13;q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Fusion protein of human RBM15
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.2 mg/mL
  
  Antigen
  
  One twenty two protein, One-twenty two protein 1, OTT, OTT1, Putative RNA-binding protein 15, RBM15, RBM15, RNA binding motif protein 15, RNA-binding motif protein 15 (UniProt:Q96T37)
  
  * For reference only.