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Overview
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Background
Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene. Has an actin-binding and actin-bundling activity. Synaptopodin is a proline-rich, actin-associated protein expressed in mature dendritic spines and renal podocytes. Synaptopodin appears to play a role in the actin-based plasticity of spines by linking actin to the spine apparatus.
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