Rabbit anti-RPL22 Polyclonal Antibody

Rabbit anti-RPL22 Polyclonal Antibody

Catalog Number:
A001085476RED
Mfr. No.:
RD85294A
Price:
$347
  • Size:
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant protein of human RPL22
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/ml
          Antigen
          60S ribosomal protein L22; EAP; EBER associated protein; EBER-associated protein; Epstein Barr encoded RNA associated protein; Epstein Barr virus small RNA associated protein; Epstein-Barr virus small RNA-associated protein; HBP15; HBP15 L22; heparin binding protein 15; Heparin binding protein HBp15; Heparin-binding protein HBp15; ribosomal protein L22; RL22; rpl22 (Gene ID:6146; UniProt:P35268)

          * For research use only.

      • Applications
        • Application
          WB

    Note: If you don't receive our verification email, do the following:

    Copyright © Amerigo Scientific. All rights reserved.