Rabbit anti-PTPRM Polyclonal Antibody (1.1mg/mL) for IHC, ELISA

Rabbit anti-PTPRM Polyclonal Antibody (1.1mg/mL) for IHC, ELISA

Catalog Number:
A001077636RED
Mfr. No.:
RD78745A
Price:
$253
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthetic peptide of human PTPRM
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1.1mg/mL
          Antigen
          hR PTPu; Protein tyrosine phosphatase mu; Protein tyrosine phosphatase receptor type M; Protein tyrosine phosphatase receptor type mu polypeptide; Protein-tyrosine phosphatase mu; PTPRL1; Ptprm; PTPRM; R PTP mu; R-PTP-mu; Receptor type tyrosine protein phosphatase mu; Receptor-type tyrosine-protein phosphatase mu; RPTPM; RPTPU (UniProt:P28827)

          * For research use only.

      • Applications
        • Application
          IHC; ELISA

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