Rabbit anti-PSMB10 Polyclonal Antibody

Rabbit anti-PSMB10 Polyclonal Antibody

Catalog Number:
A001083608RED
Mfr. No.:
RD83311A
Price:
$347
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      • Overview
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          Background

          The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein of human PSMB10
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/ml
          Antigen
          beta2i; FLJ00366; LMP10; Low molecular mass protein 10; Macropain subunit MECl 1; Macropain subunit MECl-1; MECL1; MGC1665; Multicatalytic endopeptidase complex subunit MECl 1; Multicatalytic endopeptidase complex subunit MECl-1; OTTHUMP00000174858; Proteasome (prosome macropain) subunit beta type 10; Proteasome beta 10 subunit; Proteasome catalytic subunit 2i; Proteasome MECl 1; Proteasome MECl-1; Proteasome subunit beta 2i; Proteasome subunit beta 7i; Proteasome subunit beta type 10; Proteasome subunit beta type-10; Proteasome subunit beta-2i; Proteasome subunit MECL1; PSB10; PSMB 10; Psmb10 (Gene ID:5699; UniProt:P40306)

          * For research use only.

      • Applications
        • Application
          WB; IHC; IF

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