Rabbit anti-PI 3 kinase p85 alpha Polyclonal Antibody (1.6 mg/mL) for WB

Rabbit anti-PI 3 kinase p85 alpha Polyclonal Antibody (1.6 mg/mL) for WB

Catalog Number:
A001080152RED
Mfr. No.:
RD70570A
Price:
$347
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      • Overview
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          Background

          Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer,which is composed of a P110 catalytic subunit and a P85 regulatory subunit,is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein corresponding to Human PI 3 Kinase p85 alpha.
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1.6 mg/mL
          Antigen
          GRB1; p85 alpha; p85; P85A; Phosphatidylinositol 3 kinase associated p 85 alpha; Phosphatidylinositol 3 kinase regulatory 1; Phosphatidylinositol 3 kinase; regulatory subunit; polypeptide 1 (p85 alpha); Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphoinositide 3 kinase; regulatory subunit 1 (alpha); PI3 kinase p85 subunit alpha; PI3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PI3K; PI3K regulatory subunit alpha; Pik3r1; PtdIns 3 kinase p85 alpha; PtdIns-3-kinase regulatory subunit alpha; PtdIns-3-kinase regulatory subunit p85-alpha (UniProt:P27986, P26450, Q63787)

          * For research use only.

      • Applications
        • Application
          WB

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