Name: Rabbit anti-PAX5 Polyclonal Antibody (0.5mg/mL) for WB, ELISA
Price: 253.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
- Properties
  - Host
    
    rabbit
    
    Antibody Type
    
    polyclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    human; mouse
    
    Immunogen
    
    Synthetic peptide of human PAX5
    
    Purification
    
    Affinity purification
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    
    Storage
    
    Store at -20°C. Avoid repeated freeze / thaw cycles.
    
    Concentration
    
    0.5mg/mL
    
    Antigen
    
    B cell lineage specific activator; B cell lineage specific activator protein; B cell specific activator protein; B cell specific transcription factor; B-cell-specific transcription factor; BSAP; EBB-1; KLP; Paired box 5; Paired box gene 5 (B cell lineage specific activator protein); Paired box gene 5 (B cell lineage specific activator); Paired box gene 5; Paired box homeotic gene 5; Paired box protein Pax 5; Paired box protein Pax-5; Paired domain gene 5; PAX 5; PAX5; PAX5; Transcription factor PAX 5 (UniProt:Q02548)
    
    * For research use only.
- Applications
  - Application
    
    WB; ELISA

Rabbit anti-PAX5 Polyclonal Antibody (0.5mg/mL) for WB, ELISA

Rabbit anti-PAX5 Polyclonal Antibody (0.5mg/mL) for WB, ELISA

Background

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