Name: Rabbit anti-NLRP10 Polyclonal Antibody
Price: 253.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
- Properties
  - Host
    
    rabbit
    
    Antibody Type
    
    polyclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    human
    
    Immunogen
    
    Synthetic peptide of human NLRP10
    
    Purification
    
    Affinity purification
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    
    Storage
    
    Store at -20°C. Avoid repeated freeze / thaw cycles.
    
    Concentration
    
    1.2mg/mL
    
    Antigen
    
    CLR11.1; NACHT; leucine rich repeat and PYD containing 10; NACHT; LRR and PYD domains containing protein 10; NACHT; LRR and PYD domains-containing protein 10; NAL10; NALP10; NLR family; pyrin domain containing 10; Nlrp10; NOD8; Nucleotide-binding oligomerization domain protein 8; Nucleotide-binding oligomerization domain; leucine rich repeat and pyrin domain containing 10; PAN5; PYNOD (UniProt:Q86W26)
    
    * For research use only.
- Applications
  - Application
    
    IHC; ELISA