Rabbit anti-MCM3AP Polyclonal Antibody

Rabbit anti-MCM3AP Polyclonal Antibody

Catalog Number:
A001076811RED
Mfr. No.:
RD78116A
Price:
$253
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      • Overview
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          Background

          The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Recombinant protein of human MCM3AP
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.4mg/mL
          Antigen
          80 kDa MCM3 associated protein; 80 kDa MCM3-associated protein; FLJ44336; FLJ45306; Germinal center associated nuclear protein; KIAA0572; MAP80; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 associated protein; MCM3A; MCM3A; Mcm3ap; Minichromosome maintenance complex component 3 associated protein; Minichromosome maintenance deficient 3 associated protein; Minichromosome maintenance protein 3 associated protein; Protein GANP; SAC3 (UniProt:O60318)

          * For research use only.

      • Applications
        • Application
          WB; IHC; ELISA

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