Rabbit anti-IAPP Polyclonal Antibody

Rabbit anti-IAPP Polyclonal Antibody

Catalog Number:
A001074881RED
Mfr. No.:
RD76163A
Price:
$253
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      • Overview
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          Background

          Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic peptide of human IAPP
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.8mg/mL
          Antigen
          Amylin; DAP; Diabetes associated peptide; Diabetes-associated peptide; IAP; IAPP; IAPP; Insulinoma amyloid peptide; Islet amyloid polypeptide (diabetes associated peptide; amylin); Islet amyloid polypeptide (UniProt:P10997)

          * For research use only.

      • Applications
        • Application
          IHC; ELISA

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