Name: Rabbit anti-FKBP1A Polyclonal Antibody
Price: 347.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.
- Properties
  - Host
    
    rabbit
    
    Antibody Type
    
    polyclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    human; mouse; rat
    
    Immunogen
    
    Recombinant protein of human FKBP1A
    
    Purification
    
    Affinity purification
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    
    Storage
    
    Store at -20°C. Avoid repeated freeze / thaw cycles.
    
    Concentration
    
    1mg/ml
    
    Antigen
    
    12 kDa FK506-binding protein; 12 kDa FKBP; Calstabin 1; FK506 binding protein 1; FK506 binding protein 12; FK506 binding protein 1A (12kD); FK506 binding protein 1A 12kDa; FK506 binding protein 1A; FK506 binding protein T cell 12 kD; FK506 binding protein; T cell; 12 kD; FK506 binding protein12; FK506-binding protein 1A; FKB1A; FKBP 12; FKBP 1A; FKBP-12; FKBP-1A; FKBP1; FKBP12; FKBP12 Exip3; FKBP12C; fkbp1a; Immunophilin FKBP12; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP1A; PKC12; PKCI2; PPIase; PPIase FKBP1A; Protein kinase C inhibitor 2; Rotamase (Gene ID:2280; UniProt:P62942)
    
    * For research use only.
- Applications
  - Application
    
    WB