Rabbit anti-ESPL1 Polyclonal Antibody (0.5mg/mL) for WB, IHC, ELISA

Rabbit anti-ESPL1 Polyclonal Antibody (0.5mg/mL) for WB, IHC, ELISA

Catalog Number:
A001075846RED
Mfr. No.:
RD76827A
Price:
$253
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthetic peptide of human ESPL1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.5mg/mL
          Antigen
          Caspase like protein ESPL1; Caspase-like protein ESPL1; ESP 1; ESP1; ESPL 1; Espl1; ESPL1; Extra spindle poles like 1; Extra spindle poles like 1 protein; Extra spindle poles-like 1 protein; FLJ46492; KIAA0165; Separase; Separin; Similar to fission yeast cut1and gene; SSE (UniProt:Q14674)

          * For research use only.

      • Applications
        • Application
          WB; IHC; ELISA

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