Rabbit anti-ER alpha Polyclonal Antibody (1mg/ml) for WB, IHC

Rabbit anti-ER alpha Polyclonal Antibody (1mg/ml) for WB, IHC

Catalog Number:
A001080393RED
Mfr. No.:
RD80035A
Price:
$347
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      • Overview
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          Background

          This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant protein of human ESR1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/ml
          Antigen
          DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR; ESR1; ESR1; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*; 4; 5; 6; 7*/822 isoform; Estrogen receptor alpha; Estrogen receptor alpha delta 3*; 4; 5; 6; 7*; 8*/941 isoform; Estrogen receptor alpha delta 3*; 4; 5; 6; 7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*; 5; 6; 7*/654 isoform; Estrogen receptor alpha delta 4*; 5; 6; 7; 8*/901 isoform; Estrogen receptor alpha E1 E2 1 2; Estrogen receptor alpha E1 N2 E2 1 2; Estrogen receptor; ESTRR; NR3A1; Nuclear receptor subfamily 3 group A member 1 (Gene ID:2099; UniProt:P03372)

          * For research use only.

      • Applications
        • Application
          WB; IHC

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