Name: Rabbit anti-ER alpha Polyclonal Antibody (0.6mg/mL) for IHC, ELISA
Price: 253.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
- Properties
  - Host
    
    rabbit
    
    Antibody Type
    
    polyclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    human; mouse; rat
    
    Immunogen
    
    Synthetic peptide of human ESR1
    
    Purification
    
    Affinity purification
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    
    Storage
    
    Store at -20°C. Avoid repeated freeze / thaw cycles.
    
    Concentration
    
    0.6mg/mL
    
    Antigen
    
    DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR; ESR1; ESR1; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*; 4; 5; 6; 7*/822 isoform; Estrogen receptor alpha; Estrogen receptor alpha delta 3*; 4; 5; 6; 7*; 8*/941 isoform; Estrogen receptor alpha delta 3*; 4; 5; 6; 7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*; 5; 6; 7*/654 isoform; Estrogen receptor alpha delta 4*; 5; 6; 7; 8*/901 isoform; Estrogen receptor alpha E1 E2 1 2; Estrogen receptor alpha E1 N2 E2 1 2; Estrogen receptor; ESTRR; NR3A1; Nuclear receptor subfamily 3 group A member 1 (UniProt:P03372)
    
    * For research use only.
- Applications
  - Application
    
    IHC; ELISA