Name: Rabbit anti-EIF4EBP1 Polyclonal Antibody
Price: 237.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1),is a member of 4EBPs family,which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E,thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors,hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1,alpha,beta and gamma.
- Properties
  - Host
    
    rabbit
    
    Antibody Type
    
    polyclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    human
    
    Immunogen
    
    Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 1 protein
    
    Purification
    
    Affinity purification
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
    
    Storage
    
    Store at -20°C. Avoid repeated freeze / thaw cycles.
    
    Concentration
    
    2mg/mL
    
    Antigen
    
    4E-BP1; 4EBP1; 4EBP1; BP 1; eIF4E binding protein 1; eIF4E-binding protein 1; Eif4ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; PHASI; Phosphorylated heat- and acid-stable protein regulated by insulin 1 (Gene ID:1978; UniProt:Q13541)
    
    * For research use only.
- Applications
  - Application
    
    IHC