Rabbit anti-DR1 Polyclonal Antibody

Rabbit anti-DR1 Polyclonal Antibody

Catalog Number:
A001081834RED
Mfr. No.:
RD81314A
Price:
$347
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      • Overview
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          Background

          This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant protein of human DR1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/ml
          Antigen
          Down regulator of transcription 1; Down regulator of transcription 1 TBP binding; Down-regulator of transcription 1; down-regulator of transcription 1; TBP-binding (negative cofactor 2); DR 1; Dr1; Dr1 protein; NC 2; NC2; NC2 beta; NC2-beta; NC2B; Negative co factor 2; Negative cofactor 2; Negative cofactor 2 beta; Negative cofactor 2-beta; Protein Dr1; TATA binding protein associated phosphoprotein; TATA box/binding protein associated phosphoprotein DR1; TATA-binding protein-associated phosphoprotein (Gene ID:1810; UniProt:Q01658)

          * For research use only.

      • Applications
        • Application
          WB; IHC

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