Rabbit anti-CD2AP Polyclonal Antibody

Rabbit anti-CD2AP Polyclonal Antibody

Catalog Number:
A001077831RED
Mfr. No.:
RD78946A
Price:
$253
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      • Overview
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          Background

          This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide of human CD2AP
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.2mg/mL
          Antigen
          Adapter protein CMS; AL024079; C78928; Cas ligand with multiple SH3 domains; CD2 associated protein; CD2-associated protein; CD2AP; CD2AP; CMS; Mesenchyme to epithelium transition protein with SH3 domains 1; METS 1; Mets1 (UniProt:Q9Y5K6)

          * For research use only.

      • Applications
        • Application
          WB; IHC; ELISA

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