Rabbit anti-BRK1 Polyclonal Antibody (0.2mg/mL) for IHC, ELISA

Rabbit anti-BRK1 Polyclonal Antibody (0.2mg/mL) for IHC, ELISA

Catalog Number:
A001077724RED
Mfr. No.:
RD79055A
Price:
$253
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthetic peptide of human BRK1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.2mg/mL
          Antigen
          BRICK1; SCAR/WAVE actin nucleating complex subunit; BRICK1; SCAR/WAVE actin nucleating complex subunit; homolog; BRK1; Brk1-like; C3orf10 chromosome 3 open reading frame 10; C3ORF10 GENE; Chromosome 3 open reading frame 10; Haematopoietic stem/progenitor cell protein 300; hHBrk1; HSPC300; MDS027; Probable protein BRICK1; Protein BRICK1 (UniProt:Q8WUW1)

          * For research use only.

      • Applications
        • Application
          IHC; ELISA

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