Rabbit anti-ACVR1 Polyclonal Antibody

Rabbit anti-ACVR1 Polyclonal Antibody

Catalog Number:
A001076597RED
Mfr. No.:
RD77840A
Price:
$253
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      • Overview
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          Background

          Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein of human ACVR1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.6mg/mL
          Antigen
          Activin A receptor type I; Activin A receptor type II like kinase 2; Activin receptor type I; Activin receptor type-1; Activin receptor-like kinase 2; ACTR-I; ACTRI; Acvr1; ACVR1; ACVR1A; ACVRLK2; ALK 2; ALK-2; ALK2; FOP; Hydroxyalkyl protein kinase; Serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; TGFB superfamily receptor type I; TSR-I; TSRI (UniProt:Q04771)

          * For research use only.

      • Applications
        • Application
          IHC; ELISA

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