Name: Quetiapine Fumarate
Price: 294.00 USD

- Overview
  - Quetiapine Fumarate is an inhibitor of dopamine and serotonin. Serotonin is a neurotransmitter thought to play a role in depression and schizophrenia.
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    Background
    
    Quetiapine Fumarate is a dibenzothiazepine with antagonist activity at dopamine (D1, D2, D3) and serotonin (5-HT1A and 5-HT2) receptors. It also antagonizes adrenoreceptors (alpha 1A, alpha 1b, alpha 2) and histamine receptor (H1).
- Properties
  - Categories
    
    BioActive Small Molecules
    
    CAS Number
    
    111974-72-2
    
    Molecular Formula
    
    C21H25N3O2S · 0.5C4H4O4
    
    Molecular Weight
    
    441.54
    
    Appearance
    
    White to off-white powder
    
    Solubility
    
    Slightly soluble in DMSO and DMF. slightly soluble in water.
    
    Other Properties
    
    Source: Synthetic
    Purity Level: ≥98.5%
    
    Storage
    
    2-8°C
    
    * For research use only
- Applications
  - Application Description
    
    Eukaryotic Cell Culture Applications: Quetiapine was found to alleviate oxidative stress in PC12 cells, leading to higher cell viability and a lower rate of apoptosis. These studies give new insight into the link between oxidative stress and pathophysiology of schizophrenia and Alzheimer's (Wang et al, 2005).