-
-
Overview
-
UROKINASE PLASMINOGEN ACTIVATOR (urokinase, uPA) is a key serine protease involved in the degradation of the extracellular matrix that catalyzes the conversion of plasminogen to active plasmin. It acts as a thrombolytic agent to break up blood clots and when over-expressed, has been reported to influence the growth of certain malignant tumors (breast, prostate, etc.).Our DUKI-100 Kit provides a convenient fluorimetric means to screen for potential urokinase inhibitors. In this assay, the fluorimetric substrate reacts with urokinase and an inhibitor will decrease the fluorescence at λex/em = 380/450 nm.
Key Features
▪ Safe. Non-radioactive assay.
▪ Fast. Assay is completed within a 30 minute reaction time.
▪ Homogeneous “mix-incubate-measure” type assay. Can be readily automated to assay thousands of samples per day.Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview