Pyrantel Pamoate

Pyrantel Pamoate

Catalog Number:
M001341914TOK
Mfr. No.:
TOK-P129
Price:
$171
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      • Overview
        • Pyrantel Pamoate is an anthelmintic (anti-protozoal) that was first described in 1965 by Pfizer. It is effective against intestinal nematodes (roundworm, threadworm, and hookworm, nodular worm, pinworm). The compound is soluble in DMSO.
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          Background

          Pyrantel Pamoate is an thelmintic inhibitor of BChE, and an activator of CHRNB4. It acts as a neuromuscular blocking agent, causing contraction then paralysis.

      • Properties
        • CAS Number
          22204-24-6
          Molecular Formula
          C11H14N2S•C23H16O6
          Molecular Weight
          594.68
          Appearance
          yellow to tan solid
          Solubility
          soluble in DMSO
          Other Properties
          Source: synthetic
          Storage
          2-8°C (avoid light)

          * For research use only

      • Applications
        • Application Description
          Spectrum: parasites

          Electrophoresis Applications: The synergistic effect of Pyrantel Pamoate and Metronidazole on was evaluated in the pathogenic protozoan Giardia lamblia. The in vitro effect was evaluated on its adherence to IEC-6 cells. When presented in combination, the percent adhesion was remarkable reduced, while providing low cytotoxicity to host cells (Hausen et al, 2011).

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