PURE - anti Human CD57 - HI57a

PURE - anti Human CD57 - HI57a

Catalog Number:
A001109059IMM
Mfr. No.:
57PU-01MG
Price:
$361
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • This antibody reacts with the CD57-antigen, a carbohydrate antigen present on a subset of peripheral blood mononuclear cells involved in the Natural Killer activity, which is not MHC restricted. The antigen is not present on B cells, monocytes, red blood cells or platelets but is expressed on cells in neuroectodermal tissue. It reacts with 20% of normal human peripheral blood mononuclear cells. Reacts with a 110 kDa carbohydrate antigen associated with myelin-associated glycoprotein expressed on 7-35% of normal peripheral blood lymphocytes including a subset of natural killer cells, a subset of CD8+ peripheral blood suppressor/cytotoxic T cells, and on some neural tissues.
          CD57 is not expressed on granulocytes, platelets, red blood cells or thymocytes. The function of CD57 is still unclear, however, its expression on T-cell subets occurs in late immune responses.

          Please contact us at for specific academic pricing.

      • Properties
        • Isotype
          IgM
          Reactivity
          human
          Clone
          HI57a
          Immunogen
          Human neuroblastoma cells
          Conjugate
          PURE
          Concentration
          Please refer to the Certificate of Analysis for the lot-specific concentration.
          Molecular Weight
          110 kDa
          Regulatory Status
          RUO
          Antigen
          HNK-1, NK-1, Leu-7 (Gene ID:27087)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry
          Application Description
          CD57, clone HI57a, is a mAb valid for the for identification of antigen CD57 expressed on a subset of NK cells and NK T cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
      • Reference

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