PTPN2 Polyclonal Antibody

PTPN2 Polyclonal Antibody

Catalog Number:
A001510891RED
Mfr. No.:
RD90352A
Price:
$416
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      • Overview
        • Calculated MW: 250kDa
          Observed MW: Refer to figures

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          Background

          The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Recombinant fusion protein of human PTPN2
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% proclin300,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          PTPN2, PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP, tyrosine-protein phosphatase non-receptor type 2 (Gene ID:5771; UniProt:P17706)

          * For reference only.

      • Applications
        • Application
          WB; IF
        • Application Dilutions
          WB 1:500-1:2000
          IF 1:50-1:200

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