Name: PTHrP N15 Recombinant Protein
Price: Inquiry

- Overview
  - PTHrP N15 Human Recombinant produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 86 amino acids, having an MW of 10033 Da labeled by the stable isotope N15. The PTHrP is purified by proprietary chromatographic techniques. PTHrP is a powerful and discriminating agonist of PTH2R which takes part in adenyl cyclase activation and intracellular calcium levels elevation. PTHrP encourages protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. Additionally, PTHrP inhibits cell proliferation through its contribution to PTH2R activation, activates nociceptors and nociceptive circuits and acts as a neuropeptide in spermatogenesis.
    
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- Properties
  - Protein Name
    
    Parathyroid Hormone 2, PTH2, TIPF39, Tuberoinfundibular 39 Residue Protein.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
    
    Formulation
    
    PthRp N15 protein was lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH 7.4.
    
    Storage
    
    Lyophilized PTHrP N15 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PTHrP N15 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    It is recommended to be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.

PTHrP N15 Recombinant Protein

PTHrP N15 Recombinant Protein

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