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Overview
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Threonine382/Threonine386 (T382/T386) is a major phosphorylation site of the D5 receptor. The pT382/pT386-D5 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation. T382/T386 phosphorylation is a key regulator of D5 desensitization, β-arrestin recruitment and internalization.
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