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Overview
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Serine338/Threonine339 (S338/T339) is a major phosphorylation site of the C5a1 receptor. The pS338/pT339-C5a1 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation. S338/T339 phosphorylation is a key regulator of C5a1 desensitization, β-arrestin recruitment and internalization.
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