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Overview
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Threonine342 (T342) is a major phosphorylation site of the C5a1 receptor. The pT342-C5a1 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation. T342 phosphorylation is a key regulator of C5a1 desensitization, β-arrestin recruitment and internalization.
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