PSPC1 Polyclonal Antibody (0.48 mg/mL) for IHC, ELISA

PSPC1 Polyclonal Antibody (0.48 mg/mL) for IHC, ELISA

Catalog Number:
A001508223RED
Mfr. No.:
RD252739A
Price:
$253
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      • Overview
        • Gene Accession: BC014184

          Please contact us at for specific academic pricing.

          Background

          This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human PSPC1
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.48 mg/mL
          Antigen
          Paraspeckle component 1, Paraspeckle protein 1, PSP1, Pspc1, PSPC1 (UniProt:Q8WXF1)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:30-1:150
          ELISA 1:5000-1:10000

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