PSMD12 Polyclonal Antibody (0.9 mg/mL) for WB, IHC, ELISA

PSMD12 Polyclonal Antibody (0.9 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001508236RED
Mfr. No.:
RD252752A
Price:
$253
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      • Overview
        • Calculated MW: 53 kDa
          Observed MW: Refer to figures
          Gene Accession: BC019062

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          Background

          The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human PSMD12
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.9 mg/mL
          Antigen
          26S proteasome non-ATPase regulatory subunit 12, 26S proteasome regulatory subunit p55, 26S proteasome regulatory subunit RPN5, MGC75406, p55, proteasome (prosome, macropain) 26S subunit, non ATPase12, Proteasome 26S non ATPase subunit 12 isoform 2, PSD12, PSMD12, Rpn5 (UniProt:O00232)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:1000-1:5000
          IHC 1:50-1:300
          ELISA 1:5000-1:10000

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