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Overview
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Serine435/Threonine438 (S435/T438) is a major phosphorylation site of the VPAC1 receptor. The pS435/pT438-VPAC1 antibody detects phosphorylation in response to high-efficacy agonists. S422/S425 phosphorylation is a key regulator of VPAC1 desensitization, β-arrestin recruitment and internalization. S435/T438 also undergoes constitutive phosphorylation.
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Overview