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Overview
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Serine361 (T361) is a major phosphorylation site of the somatostatin receptor 3 (SST3). The pS361-SST3 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation. S361 phosphorylation is a key regulator of SST3 desensitization, β-arrestin recruitment and internalization.
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Overview