PPP2R4 Rabbit Polyclonal Antibody

PPP2R4 Rabbit Polyclonal Antibody

Catalog Number:
A001452362ZEN
Mfr. No.:
Zen-826417
Price:
  • Size:
    100μl
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Fusion protein of human PTPA
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 41 kDa; Observed MW: 41 kDa
          Antigen
          (Gene ID:5524; UniProt:Q15257)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/100

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