PPBP Polyclonal Antibody (0.8 mg/mL) for WB, IHC, ELISA

PPBP Polyclonal Antibody (0.8 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001507284RED
Mfr. No.:
RD219288A
Price:
$253
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      • Overview
        • Calculated MW: 14 kDa
          Observed MW: Refer to figures
          Gene Accession: NP002695

          Please contact us at for specific academic pricing.

          Background

          PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Colloid Adenoma. Among its related pathways are GPCR Pathway and Peptide ligand-binding receptors. GO annotations related to this gene include growth factor activity and glucose transmembrane transporter activity. An important paralog of this gene is CXCL1. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide of human PPBP
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.8 mg/mL
          Antigen
          B TG1, Beta TG, Beta thromboglobulin, Beta-TG, C-X-C motif chemokine 7, Chemokine (C X C motif) ligand 7, Connective tissue activating peptide III, CTAP 3, CTAP III, CTAP-III, CTAP-III(1-81), CTAP3, CTAPIII, CXC chemokine ligand 7, CXCL 7, CXCL7, CXCL7, LA PF 4, LA-PF4, LDGF, Leukocyte derived growth factor, Leukocyte-derived growth factor, Low-affinity platelet factor IV, Macrophage-derived growth factor, MDGF, NAP 2, NAP-2, NAP-2(1-63), NAP-2(1-66), NAP-2(73), NAP-2(74), Neutrophil activating peptide 2, Neutrophil-activating peptide 2(1-63), PBP, Platelet basic protein, PPBP, Pro platelet basic protein (chemokine (C-X-C motif) ligand 7), Pro platelet basic protein, SCYB7, Small inducible cytokine subfamily B member 7, Small-inducible cytokine B7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, Thrombocidin 1, Thrombocidin 2, Thromboglobulin, beta-1 (UniProt:P02775)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:1000-1:5000
          IHC 1:25-1:100
          ELISA 1:2000-1:10000

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