PON3/paraoxonase 3 Polyclonal Antibody

PON3/paraoxonase 3 Polyclonal Antibody

Catalog Number:
A001511896RED
Mfr. No.:
RD86662A
Price:
$237
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      • Overview
        • Calculated MW: 21kDa
          Observed MW: 21kDa

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          Background

          The paraoxonase (PON) gene family of antioxidant enzymes includes three known members located adjacent to each other on chromosome 7. Paraoxonase/lactonase 3 (PON3) is a 354 amino acid, 39.6 kDa protein that is secreted into the bloodstream and associates with high-density lipoprotein (HDL). PON3 has lactonase activity (EC 3.1.1) and rapidly hydrolyzes lactones. PON3 exhibits no paraoxonase and very limited arylesterase activities. PON3 is an important antioxidant and can inhibit the oxidation of low-density lipoprotein (LDL), a function that may slow the initiation and progression of atherosclerosis.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          mouse; rat
          Immunogen
          Recombinant Human PON3 protein expressed by E.coli.
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol,pH 7.4
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          2mg/mL
          Antigen
          Serum paraoxonase/lactonase 3, PON3 (Gene ID:5446; UniProt:Q15166)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:1000-1:2000

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