Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-N-hydroxysuccinimide endcap

Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-N-hydroxysuccinimide endcap

Catalog Number:
PG01436030AKI
Mfr. No.:
AKI-AI064
Price:
$450
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      • Overview
        • Contain chemically active or activatable endgroups for you to graft on to your own polymer or system of choice. Useful for targeted delivery and immunotherapy applications.​ Note for indicated block copolymers "(w:w)" denotes that the ratio shown is based on component weight rather than molar content.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Intermediates
          Alternative Name
          PLGA-PEG-NHS
          Other Properties
          LG 50:50 (Mw ~17,000:3,000 Da)

          * For Research Use Only

      • Applications
        • Application
          Customer functionalization for visualization or endcapping
      • Reference
        • 2023
          Leach, Adam, Marie Finnegan, Mariana Stefani Machado, Laura Ferguson, John Steven, Peter Smyth, Andrew Porter, Caroline Barelle, Efrosyni Themistou, and Christopher J. Scott. "Functionalization of polymeric nanoparticles with targeting VNAR ligands using vinyl sulfone conjugation".Journal of Materials Chemistry B2023
          Product Usage: Nanoparticle Shell

          2020
          Greene, Michelle, João CF Nogueira, Shannon R. Tracey, Daniel A. Richards, William McDaid, James F. Burrows, Katrina Campbell, Dan Longley, Vijay Chudasama, and Christopher J. Scott. "Refined construction of antibody-targeted nanoparticles leads to superior antigen binding and enhanced delivery of an entrapped payload to pancreatic cancer cells".Nanoscale(2020).
          Product Usage: Decorated Nanoparticle Shell
          Johnston, M.C., Nicoll, J.A., Redmond, K.M., Smyth, P., Greene, M.K., McDaid, W.J., Chan, D.K.W., Crawford, N., Stott, K.J., Fox, J.P. and Straubinger, N.L.. "DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models".Journal of Controlled Release2020.
          Product Usage: Decorated Nanoparticle Shell
          Khang, Min Kyung, Aneetta Elizabeth Kuriakose, Tam Nguyen, Cynthia My-Dung Co, Jun Zhou, Thuy Thi Dang Truong, Kytai Truong Nguyen, and Liping Tang. "Enhanced Endothelial Cell Delivery for Repairing Injured Endothelium via Pretargeting Approach and Bioorthogonal Chemistry".ACS Biomaterials Science & Engineering(2020)
          Product Usage: Decorated Nanoparticle Shell

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