Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-maleimide | LG 50:50 (10,000:5,000 Da)

Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-maleimide | LG 50:50 (10,000:5,000 Da)

Catalog Number:
PG01436021AKI
Mfr. No.:
AKI-AI053
Price:
$432
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      • Overview
        • Contain chemically active or activatable endgroups for you to graft on to your own polymer or system of choice. Useful for targeted delivery and immunotherapy applications.​ Note for indicated block copolymers "(w:w)" denotes that the ratio shown is based on component weight rather than molar content.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Intermediates
          Alternative Name
          Poly(Lactic-co-glycolic acid)-Poly(ethylene glycol)-maleimide; PLGA-PEG-Mal
          Other Properties
          LG 50:50 (Mw ~10,000:5,000 Da)

          * For Research Use Only

      • Applications
        • Application
          Customer endcapping with peptide ligands (must contain free thiol)
      • Reference
        • 2023
          Hadley, Pierce, Yuanzhou Chen, Lariana Cline, Zhiyuan Han, Qizhi Tang, Xiao Huang, and Tejal Desai. "Precise surface functionalization of PLGA particles for human T cell modulation".Protocol Exchange(2023)
          Product Usage: Decorated Nanoparticle Shell

          2021
          Huang, Xiao, Jasper Z. Williams, Ryan Chang, Zhongbo Li, Cassandra E. Burnett, Rogelio Hernandez-Lopez, Initha Setiady et al.. "DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation".Nature Nanotechnology16, no. 2 (2021): 214-223
          Product Usage: Decorated Nanoparticle Shell
          Levy, Elizabeth S., Ryan Chang, Colin R. Zamecnik, Miqdad O. Dhariwala, Lawrence Fong, and Tejal A. Desai. "Multi-Immune Agonist Nanoparticle Therapy Stimulates Type I Interferons to Activate Antigen-Presenting Cells and Induce Antigen-Specific Antitumor Immunity".Molecular Pharmaceutics(2021).
          Product Usage: Decorated Nanoparticle Shell
          Na Kyeong, Chi-Pin James Wang, Jaesung Lim, Wooram Park, Ho-Keun Kwon, Se-Na Kim, Tae-Hyung Kim, and Chun Gwon Park. "Impact of the conjugation of antibodies to the surfaces of polymer nanoparticles on the immune cell targeting abilities".Nano Convergence8, no. 1 (2021): 1-11.
          Product Usage: Decorated Nanoparticle Shell

          2020
          Dancy, Jimena G., Aniket S. Wadajkar, Nina P. Connolly, Rebeca Galisteo, Heather M. Ames, Sen Peng, Nhan L. Tran et al. "Decreased nonspecific adhesivity, receptor-targeted therapeutic nanoparticles for primary and metastatic breast cancer".Science Advances6, no. 3 (2020): eaax3931
          Product Usage: Decorated Nanoparticle Shell

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