Name: Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-maleimide | (20,000:5,000 Da)
Price: 432.00 USD

- Overview
  - Contain chemically active or activatable endgroups for you to graft on to your own polymer or system of choice. Useful for targeted delivery and immunotherapy applications. Note for indicated block copolymers "(w:w)" denotes that the ratio shown is based on component weight rather than molar content.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Intermediates
    
    Alternative Name
    
    Poly(Lactic-co-glycolic acid)-Poly(ethylene glycol)-maleimide; PLGA-PEG-Mal
    
    Other Properties
    
    (20,000:5,000 Da)
    
    * For Research Use Only
- Applications
  - Application
    
    Customer endcapping with peptide ligands (must contain free thiol)
- Reference
  - 2023
    McDaid, William J., Nikolai Lissin, Ellen Pollheimer, Michelle Greene, Adam Leach, Peter Smyth, Giovanna Bossi, Daniel Longley, David K. Cole, and Christopher J. Scott. . "Enhanced target-specific delivery of docetaxel-loaded nanoparticles using engineered T cell receptors".Nanoscale13, no. 35 (2021): 15010-15020
    Product Usage: Decorated Nanoparticle Shell
    
    2021
    Li, Peter Y., Frank Bearoff, Pu Zhu, Zhiyuan Fan, Yucheng Zhu, Mingyue Fan, Laura Cort, Taku Kambayashi, Elizabeth P. Blankenhorn, and Hao Cheng. "PEGylation enables subcutaneously administered nanoparticles to induce antigen-specific immune tolerance".Journal of Controlled Release2021
    Product Usage: Decorated Nanoparticle Shell
    Ni, Ling, and You-Xin Li. "Anti-Human Epidermal Growth Factor Receptor 2 Single-Chain Fv Fragment-Decorated DM1 Nanoparticles for Specific Targeting of Human Epidermal Growth Factor Receptor 2-Positive Breast Tumor Cells".Journal of Biomedical Nanotechnology17, no. 3 (2021): 447-455.
    Product Usage: Decorated Nanoparticle Shell
    
    2020
    Holley, C. K., and S. Majd. "Examining the Anti-Tumor Activity of Dp44mT-Loaded Nanoparticles In Vitro".2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)pp. 5029-5032. IEEE, 2020.
    Product Usage: Decorated Nanoparticle Shell
    Kang, You Jung, Claire K. Holley, Mohammad Reza Abidian, Achuthamangalam B. Madhankumar, James Connor, and Sheereen Majd. "Tumor Targeted Delivery of an Anti‐Cancer Therapeutic: An In Vitro and In Vivo Evaluation".Advanced Healthcare Materials(2020): 2001261
    Product Usage: Decorated Nanoparticle Shell
    Martínez-Jothar, Lucía, Arjan D. Barendrecht, Anko M. de Graaff, Sabrina Oliveira, Cornelus F. van Nostrum, Raymond M. Schiffelers, Wim E. Hennink, and Marcel HAM Fens. . "Endothelial Cell Targeting by cRGD-Functionalized Polymeric Nanoparticles under Static and Flow Conditions".Nanomaterials10, no. 7 (2020): 1353.
    Product Usage: Decorated Nanoparticle Shell