Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) | (1,000:1,000:1,000 Da) LA:GA 50:50

Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) | (1,000:1,000:1,000 Da) LA:GA 50:50

Catalog Number:
PG01436202AKI
Mfr. No.:
AKI-AK012
Price:
$407
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      • Overview
        • Block copolymers synthesized so as to contain both biodegradable blocks and hydrophilic blocks. Can be used for a wide range of purposes.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Block Copolymers
          Alternative Name
          Poly(lactic-co-glycolic acid)-b-Poly(ethylene glycol)-b-Poly(lactic-co-glycolic acid); PLGA-PEG-PLGA
          Other Properties
          (Mw ~1,000:1,000:1,000 Da) LA:GA 50:50

          * For Research Use Only

      • Applications
        • Application
          Thermogelation
      • Reference
        • 2023
          Kim, Seo Yeon, Min Jeong Jo, Moon Sup Yoon, Chae Eun Jin, Yu Been Shin, Jae Min Lee, Hee Ji Shin et al. "Gemcitabine and rapamycin-loaded mixed polymeric thermogel for metastatic pancreatic cancer therapy".Journal of Controlled Release360 (2023): 796-809.
          Product Usage: Thermogel
          Rahman, Sadia, Tasmima N. Haque, Vrashabh V. Sugandhi, Aishwarya L. Saraswat, Xiaoban Xin, and Hyunah Cho. "Topical Cream Carrying Drug-Loaded Nanogels for Melanoma Treatment".Pharmaceutical Research(2023): 1-11
          Product Usage: Thermogel
          Shirasu, Takuro, Nisakorn Yodsanit, Jing Li, Yitao Huang, Xiujie Xie, Runze Tang, Qingwei Wang et al.. "Neointima abating and endothelium preserving—An adventitia-localized nanoformulation to inhibit the epigenetic writer DOT1L".Biomaterials(2023): 122245.
          Product Usage: Thermogel
          Zhang, Mengxue, Jing Li, Qingwei Wang, Go Urabe, Runze Tang, Yitao Huang, Jose Verdezoto Mosquera et al. . "Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation".Molecular Therapy-Nucleic Acids(2023)
          Product Usage: Thermogel

          2022
          Zhang, Mengxue, Go Urabe, Hatice Gulcin Ozer, Xiujie Xie, Amy Webb, Takuro Shirasu, Jing Li et al. . "Angioplasty induces epigenomic remodeling in injured arteries".Life Science Alliance5, no. 5 (2022)
          Product Usage: Thermogel

          2021
          Li, Jing, Go Urabe, Yitao Huang, Mengxue Zhang, Bowen Wang, Lynn Marcho, Hongtao Shen, K. Craig Kent, and Lian-Wang Guo. "A role for polo-like kinase 4 in vascular fibroblast cell-type transition".Basic to Translational Science6, no. 3 (2021): 257-283
          Product Usage: Thermogel

          2020
          Byrne, Mark E., Mindy George-weinstein, and Laura L. Osorno. "Optically Clear, in-situ Forming Biodegradable Nano-Carriers For Ocular Therapy, and Methods Using Same".U.S. Patent Application16/498,689, filed February 6, 2020
          Product Usage: Thermogel
          Gong, Zhe, Chenggui Wang, Licheng Ni, Liwei Ying, Jiawei Shu, Jingkai Wang, Chao Yu et al.. "An injectable recombinant human milk fat globule–epidermal growth factor 8–loaded copolymer system for spinal cord injury by reducing inflammation through NF-κB pathway and neuronal cell death".Cytotherapy(2020)
          Product Usage: Thermogel
          Huang, Yitao, Go Urabe, Mengxue Zhang, Jing Li, Hatice Gulcin Ozer, Bowen Wang, K. Craig Kent, and Lian-Wang Guo. "Nullifying epigenetic writer DOT1L attenuates neointimal hyperplasia".Atherosclerosis308 (2020): 22-31
          Product Usage: Thermogel
          Wang, Bowen, Mengxue Zhang, Go Urabe, Takuro Shirasu, Lian-Wang Guo, and K. Craig Kent. "PERK Inhibition Promotes Post-angioplasty Re-endothelialization via Modulating SMC Phenotype Changes".Journal of Surgical Research257: 294-305.
          Product Usage: Thermogel
          Zhang, Mengxue, Bowen Wang, Go Urabe, Gulcin Ozer, Renzhi Han, Craig Kent, and Lianwang Guo.. "Angioplasty-induced epigenomic remodeling entails BRD4 and EZH2 hierarchical regulations".bioRxiv2020
          Product Usage: Thermogel

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