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Overview
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Calculated MW: 22kDa/33kDa
Observed MW: 35KDaPlease contact us at for specific academic pricing.
Background
3'-exoribonuclease that has a preference for poly(A tails of mRNAs, thereby efficiently degrading poly(A tails. Exonucleolytic degradation of the poly(A tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells (By similarity.
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