PMP70/ABCD3 Polyclonal Antibody

PMP70/ABCD3 Polyclonal Antibody

Catalog Number:
A001510784RED
Mfr. No.:
RD89024A
Price:
$416
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      • Overview
        • Observed MW: 30kDa

          Please contact us at for specific academic pricing.

          Background

          The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human PMP70/ABCD3
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          ABC43, CBAS5, PMP70, PXMP1, ZWS2, ABCD3 (Gene ID:5825; UniProt:P28288)

          * For reference only.

      • Applications
        • Application
          WB; IHC; IF
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200
          IF 1:50-1:200

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