Name: PLP (139-151)
Price: 238.00 USD

- Overview
  - Induces severe experimental allergic encephalomyelitis (EAE).
    PLP (139-151), or proteolipid protein (139-151) is a myelin proteolipid protein (PLP) fragment. PLP is one of the major protein constituents of myelin, along with myelin oligodendrocyte glycoprotein (MOG) and myelin basic protein (MBP), which between them make up 15% – 25% of dry weight, the rest being mainly lipids. Myelin has an essential insulating role for nerves, allowing normal motor function, sensory function and cognition. Animals immunized with PLP (139-151) develop severe experimental allergic encephalomyelitis (EAE) and this model is widely used to study human multiple sclerosis (MS).
    
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- Properties
  - Categories
    
    Myelin Peptides
    
    Alternative Name
    
    Proteolipid protein (139-151)
    
    Molecular Formula
    
    C72H104N20O16S
    
    Molecular Weight
    
    1537.8
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in dilute acid
    
    Other Properties
    
    Sequence: H-His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH,HCLGKWLGHPDKF
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

PLP (139-151)

PLP (139-151)

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