Pitavastatin

Pitavastatin

Catalog Number:
L002369828APE
Mfr. No.:
APE-B1124
Price:
$172
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Pitavastatin (NK-104) is a potent HMG-CoA reductase inhibitor, Pitavastatin inhibited cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in a human liver cancer cell line (HepG2).

      • Properties
        • Alternative Name
          (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
          CAS Number
          147511-69-1
          Molecular Formula
          C25H24FNO4
          Molecular Weight
          421.46
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          ≥10.56 mg/mL in H2O with ultrasonic; ≥14.35 mg/mL in DMSO; ≥8.46 mg/mL in EtOH with ultrasonic
          Storage
          Store at -20°C

          * For Research Use Only

      • Reference
        • 1. Jie Yang, Mengjia Sun, et al. "Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice." Commun Biol. 2022 Feb 10;5(1):124. PMID:35145192

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