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Overview
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PIP4K2B Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 439 amino acids (1-416 a.a) and having a molecular mass of 49.8kDa. PIP4K2B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, Beta (PIP4K2B) belongs to the phosphatidylinositol-4-phosphate 5-kinase family. PIP4K2B catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the 5th hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. PIP4K2B amino acid sequence does not show resemblance to another kinases although PIP4K2B presents kinase activity. PIP4K2B also interacts with p55 TNF receptor.
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Overview