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Overview
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It produced in E.coli is a single, non-glycosylated polypeptide chain containing 495 amino acids (1-472) andhaving a molecular mass of 56.1kDa.phrB is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Deoxyribodipyrimidine photo-lyase (phrB) is a member of the DNA photolyase class-1 family. phrB takes part in repair of UV radiation-inducedDNA damage. phrB catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between closest bases on the same DNA strand upon exposure to ultraviolet radiation.
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- Properties
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Overview