Phospho-c-Fos (Ser362) Rabbit Polyclonal Antibody

Phospho-c-Fos (Ser362) Rabbit Polyclonal Antibody

Catalog Number:
A001449222ZEN
Mfr. No.:
Zen-370314
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          The c-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phospho-protein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Functional homologs of c-Fos include the Fra-1, Fra-2 and Fos B genes. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Serine 362.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
          Antigen
          (Gene ID:2353; UniProt:P01100)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/200

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