Phase II Metabolic Stability Kit, Species: Monkey, Gender: Female

Phase II Metabolic Stability Kit, Species: Monkey, Gender: Female

Catalog Number:
IVAP465183IPH
Mfr. No.:
iPh-0112B1.02
Price:
  • Size:
    0.2mL*50 test
    Quantity:
    Add to Cart:
      • Overview
        • Phase II metabolism, also known as the binding reaction, refers to the reaction in which phase I metabolites or prototype drugs combine with endogenous small molecules via phase II enzymes, leading to the reduction of toxicity, activity, or polarity of prodrugs. In phase II metabolism, the most common reaction is glucuronidation, during which the uridine diphosphate glucuronic acid (UDPGA) is bound to the prodrug via catalyzation by glucuronyl transferase in microsomes. The glucuronide formed increases water-solubility of metabolites to enhance the excretion. The phase II metabolic system can be reconstructed by combination of liver microsomes and UGT and used to study phase II metabolic stability of drug candidates in vitro.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Phase II Metabolic Stability Kits
          Formulation
          Microsome|Substrate| UGT Incubation System| 0.1M PBS (pH7.4)
          Storage
          Store at -70°C. Dry ice delivered.

          * For research use only.

      • Applications
        • Application
          In vitro Assessment of Metabolic Stability

    Note: If you don't receive our verification email, do the following:

    • Confirm that you entered your email address correctly.
    • Check if the email is in your spam or junk folder.
    • Or you may contact us at .
    Copyright © Amerigo Scientific. All rights reserved.