Perkit™ Peptide-oligo Conjugation kit

This is a custom kit made to order. The kit materials and user manual will be supplied to you based on your oligo length, peptide sequence, and peptide length. Please supply this information when you place the order.

This personalized peptide-oligo conjugation kit is designed to work with any peptide with an accesible Cys residue and any amine-modified oligo. The customer supplies the peptide and amine-modified oligo (readily available from many commercial oligo suppliers). If the peptide sequence doesn't contain a Cys residue, an extra Cys should be added to the peptide sequence either at the C-terminal or N-terminal as a linker. Using the kit components, the customer converts the amine-oligo to a maleimide-oligo, followed by a reaction of the maleimide oligo with thiol-peptide to generate the conjugates. A One-step purification process then typically provides the resulting peptide-oligo conjugate at greater than 80% purity.

This kit provides materials to perform one (CM42301x1) or three (CM42301x3) conjugations.

• Requirement for peptide
Sequence: add a Cys residue either at the C-terminal or N-terminal for labeling
Amount: 1-5 mg depending on the peptide MW
HPLC purified and lyophilized. Please make sure there is no reducing reagents, such as DTT are present. The Cys peptide should be stored at -80°C.
HPLC purity: >85% for N-terminal Cys peptide and >90% for C-terminal Cys peptide

• Requirement for amine-oligo
Amount: 50 nmol
HPLC purified and lyophilized
Additional components of acid or other molecules containing primary or secondary amine groups and thiol should NOT be present

• Key Features of this Peptide-Oligo Conjugation Kit
Offers a simple and easy way to prepare oligo-peptide conjugate
Single label
Fast and easy preparation: 6 h preparation and <2 h hands-on time
All reagents and supplies included for preparation to purification

Please contact us at for specific academic pricing.