PerKit™ KLH Small Molecule Acid Conjugation Kit

Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein for antibody production. KLH is a large, oxygen-carrying, and multi-subunit protein that contains chelated copper of non-heme origin. This personalized KLH conjugation kit is designed to work with any small molecule containing a carboxylic acid (-COOH) functional group. Using the kit components, the customer converts the carboxylic acid to an activated N-hydroxysuccinimide (NHS) ester, followed by reaction with the surface amino groups of the protein to form a stable amide bond. The final product is purified to remove any unreacted small molecule acid.

This kit provides materials to perform one KLH labeling. Total amount of KLH included: 5 mg.

• Requirement for Small Molecule
Preferably > 90% pure
Absence of primary or secondary amine (-NH2) groups
Preferably contains only one non-hindered aliphatic carboxylic acid (-COOH)
For molecule containing aromatic carboxylic acid, hindered aliphatic carboxylic acid, or hydroxyl (-OH) groups, please consult us first before placing the order.

• Key Features of this PerKit™
Offers a simple and easy way to label KLH with any small molecule containing carboxylic acid
Fast and easy preparation: 4 h preparation and <30 minutes hands-on time
All reagents and supplies included for preparation and purification
Over 90% pure conjugated products by SEC

Please contact us at for specific academic pricing.