Oxoglutarate Receptor 1 - ExpressMAX™ Human GPCR ORF Clones

Oxoglutarate Receptor 1 - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268594CAN
Mfr. No.:
G0635-B; G0635-Plus
Price:
$579
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      • Overview
        • Human Oxoglutarate (alpha-ketoglutarate) Receptor 1 (OXGR1) is encoded by the OXGR1 gene that is expressed in kidney and, to a lower extend, in placenta, not detected in brain tissues. It is a member of the GPCR family and is similar to the Purinergic P2Y receptors. OXGR1 is receptor for alpha-ketoglutarate, an intermediate in the citric acid cycle. Because OXGR1 activation did not affect cAMP levels and both inositol phosphate formation and calcium ion flux were found to be insensitive to pertussis toxin, this receptor seems to act exclusively through a G(q)-mediated pathway.

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Expression-ready Human GPCR ORF Clones
          Other Properties
          Plasmid size: 6353 bp
          Promoter: pMLV
          ORF Sequence (GenBank based): NM_080818.3
          Protein Sequence (SwissProt): Q96P68
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: aKGR, GPR80, GPR99, P2Y15 or P2RY15
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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